INSULIN-LIKE GROWTH FACTOR IGF-1 LONG R3, NORDEX

INSULIN-LIKE GROWTH FACTOR IGF-1

IGF-1 as such was discovered in 1978 and after 10 years it began to be used by athletes. It has gained immense popularity due to the fact that it does not need additional supplements at all (steroid courses, insulin, etc.). But recently, side effects have also been bred: an increase in the liver, spleen, the number of malignant cells

Insulin-like growth factor 1 (IGF-1, somatomedin C) is a protein from the family of insulin-like growth factors, similar in structure and function to insulin. It is involved in the endocrine, autocrine and paracrine regulation of the processes of growth, development and differentiation of cells and tissues of the body.

IGF-1 provides feedback to the hypothalamus and pituitary along the somatotropic axis: the secretion of somatotropin-releasing hormone and somatotropic hormone depends on the level of IGF-1 in the blood. With a low level of IGF-1 in the blood, the secretion of somatotropin-releasing hormone and somatotropin increases, and with a high level, it decreases. The level of IGF-1 in the blood depends on the effect on the liver of not only growth hormone, but also sex steroids and thyroid hormones, glucocorticoids, and insulin. At the same time, insulin, androgens, estrogens increase the secretion of IGF-1 by the liver, and glucocorticoids reduce it. This is one of the reasons for the synergism of insulin, somatotropin, sex and thyroid hormones in relation to the processes of growth and development of the body, growth and differentiation of tissues, and one of the reasons for the characteristic inhibitory effect of glucocorticoids on the processes of linear growth, puberty, etc. IGF-1 affects development throughout life, but its blood level is not constant: the lowest level of IGF-1 production in childhood and old age, and the highest during adolescence.

Apply - before training 100-300 mcg.